CAS:
23288-49-5
Molecular
Formula: C31H48O2S2
Molecular
weight:516.8416
Probucol
is alone begin in individuals that accept used or taken this drug. It is a
biologic used to lower LDL and HDL cholesterol yet has little aftereffect on
serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra
Pharmacopoeia, 30th ed, p993). Probucol lowers serum cholesterol by accretion
the apportioned amount of low-density lipoprotein (LDL) catabolism in the final
metabolic alleyway for cholesterol abolishment from the body. Additionally,
probucol may arrest aboriginal stages of cholesterol biosynthesis and hardly
arrest comestible cholesterol absorption. Recent advice suggests that probucol
may arrest the blaze and tissue degradation of LDL cholesterol, thereby
inhibiting atherogenesis. It appears to inhibits ABCA1-mediated cellular lipid
efflux.
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