Fluconazole
is an antifungal medication used in the analysis of several fungal infections.
The drug is used orally and intravenously. Fluconazole broadly distributes into
physique tissues, nails and fluids including saliva, sputum, vaginal
secretions. Fluconazole does not abide aboriginal canyon metabolism and is
excreted mostly in the urine and some in the feces. This drug can aswell be used
in the pediatric population.
With
its different mechanisms of action, fluconazole has accustomed a ample breadth
of advantage in both dermatological and non-dermatological diseases.
Fluconazole has acceptable advantage adjoin candida. Because it can access the
CSF, it can be used to amusement cryptococcal meningitis. Other
non-dermatological diseases it treats are esophageal candidiasis, float
candidiasis, systemic candidiasis, fungal prophylaxis in cartilage bottom
transplant, cystitis, urinary amplitude infections, and intra-abdominal
infections. There are some added off-label uses for fluconazole including
analysis of blastomycosis, coccidiomycosis, and histoplasmosis.
Secondary
to its apparatus of action, fluconazole finds account in the afterward
dermatologic diseases:
Vulvovaginal
candidiasis
Oral
candidiasis
Mucocutaneous
candidiasis
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