What is Cycloheximide?

CAS No.: 66-81-9

Molecular Formula: C15H23NO4

Molecular Weight: 281.35

Cycloheximide is a awful able antibacterial with action adjoin mold, yeast, and phytopathogenic fungi, with lower action adjoin bacteria. It has been appear to arrest the amalgam of both proteins and macromolecules, as able-bodied as affect apoptosis in eukaryotes. Inhibition of protein amalgam is believed to be advised through DNA adaptation arrest, as approved in rat thymocytes.

Although cycloheximide has been appear to abet apoptosis in assorted cells, it has aswell been apparent to arrest or adjournment induced apoptosis. These observations advance that cycloheximide's aftereffect on apoptosis may not be alone through protein adaptation arrest and that added mechanisms may be involved. Cycloheximide has aswell been appear to arrest FKBP12 via aggressive inhibition.