Sunday, July 23, 2017

What is Triethyl phosphonoacetate?


CAS: 867-13-0
Molecular Formula: C8H18O11P3
Molecular weight:383.1438
Triethyl phosphonoacetate is a reagent for amoebic amalgam used in the Horner-Wadsworth-Emmons acknowledgment (HWE) or the Horner-Emmons modification.

Triethyl phosphonoacetate can be added dropwise to sodium methoxide band-aid to adapt a phosphonate ylide. It has an acerb proton that can calmly be absent by a anemic base. When used in an HWE acknowledgment with a carbonyl the consistent alkene formed is usually the E alkene, and is generated with accomplished regioselectivity.

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